By Jayesh Mehta, Seema Singhal
With contributions from foreign specialists, Myeloma presents a entire assessment of a number of myeloma and comparable plasma-cell problems. It examines the molecular and organic heritage of those illnesses, in addition to their scientific facets and investigations, and advancements in treatment. Containing a hundred and fifty colour illustrations, charts, and graphs, the publication summarizes useful functions of cytogenetic reviews in plasma-cell dyscrasias, covers the pathology of myeloma bone affliction, discusses the present methods of assessing skeletal involvement, and highlights using new biophosphonates. this article is a pragmatic reference for hematologists, oncologists, and researchers.
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Extra resources for Myeloma
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The figure shows just some of the proteins encoded by genes that have been implicated in the molecular pathogenesis of myeloma. functions, thus exemplifying the complexity of rational drug design. Further understanding of the transformation process and the pathways involved in malignant progression is essential to the development of effective therapeutic agents. 2. 3. REFERENCES 4. 1. Pope B, Brown R, Luo XF, et al. Disease progression in patients with multiple myeloma is associated with a concurrent alteration in the expression of both oncogenes and tumor suppressor genes and can be monitored by the oncoprotein phenotype.