Anemia in the Elderly by Lodovico Balducci, William B. Ershler, John M. Bennett

By Lodovico Balducci, William B. Ershler, John M. Bennett

Anemia within the aged has been appropriately outlined because the silent epidemic, representing three million humans within the usa elderly sixty five years and older. occurrence and incidence of this situation bring up with age. It differs in its etiology, pathogenesis and remedy from anemia in youngsters and more youthful adults. Anemia is linked to lowered survival, elevated threat of useful dependence and hospitalization, elevated hazard of congestive middle failure and degree renal illness and cognitive issues. nearly 70% of anemia in older members is reversible.

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Example text

5). As shown in Fig. 4, according to the study of Andres et al. 4 µmol/mL in the absence of renal failure or folate and B6 deficiency. However, as pointed out by Solomon, there is considerable uncertainty about the diagnostic criteria and probably no one single laboratory value is sufficient (11). 6 (from 10). Food cobalamin malabsorption is characterized by the inability to release cobalamin from food or from intestinal transport proteins, particularly in the presence of hypochlorhydria. This syndrome is defined by the presence of cobalamin deficiency despite an adequate diet.

2006;54:1429–35 67. Penninx BW, Pluijm SM, Lips P et al: Late life anemia is associated with increased risk of recurrent falls. J Am Geriatr Soc. 2005;53:2106–111 68. Bohlius J, Langersiepen S, Schwarzer G et al: Recombinant human erythropoietin and overall survival in cancer patients. Results of a comprehensive meta-analysis. J Natl Cancer Inst. 2005;97:489–98 69. Norman EJ, Morrison JA: Screening elderly populations for cobalamin (vitamin B12) deficiency using the urinary methylmalonic acid assay by gas chromatography mass spectrometry.

In the case of anemia of aging or other forms of ACI the benefits of erythropoietin should be explored in randomized controlled study having as end-points survival, compression of morbidity, and preservation of independence. Conclusions Anemia becomes more common with age and is associated with decreased survival, functional dependence, coronary deaths, congestive heart failure, and a number of geriatric syndromes, including dementia delirium, depression and falls. 2. Anemia and Aging or Anemia of Aging?

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